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《医学前沿(英文)》 2023年 第17卷 第4期 页码 685-698 doi: 10.1007/s11684-022-0942-1
关键词: acute myeloid leukemia acyl-CoA synthetase long chain family member 5 Wnt3a palmitoylation ABT-199
Keratin 5-Cre-driven deletion of
Jun Yang, Lianqing Wang, Yingzhi Huang, Keqiang Liu, Chaoxia Lu, Nuo Si, Rongrong Wang, Yaping Liu, Xue Zhang
《医学前沿(英文)》 2020年 第14卷 第3期 页码 305-317 doi: 10.1007/s11684-019-0722-8
关键词: acne inversa mouse model interleukin 1 family member 6 small proline rich protein 2D key inflammatory cytokine
Zhuoying WU, Qing WANG, Feng GUO, Shenghua ZHANG, Qipei JIANG, Xin YU
《环境科学与工程前沿(英文)》 2014年 第8卷 第2期 页码 205-214 doi: 10.1007/s11783-013-0492-5
关键词: drinking water distribution systems (DWDS) biofilm quorum sensing (QS) N-acyl-L-homoserine lactones (AHLs) (dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) 2(5H)-furanone
Benzene alkylation with long chain olefins catalyzed by ionic liquids: a review
QIAO Congzhen, CAI Yonghong, GUO Quanhui
《化学科学与工程前沿(英文)》 2008年 第2卷 第3期 页码 346-352 doi: 10.1007/s11705-008-0045-9
关键词: different petrochemical characterization introduction chloroaluminate
QIAO Congzhen, LI Chengyue
《化学科学与工程前沿(英文)》 2008年 第2卷 第1期 页码 69-73 doi: 10.1007/s11705-008-0014-3
关键词: stability different hypecritical compulsive mixing-reacting-separating-recycling non-benzene
龙乐豪,王小军,果琳丽
《中国工程科学》 2006年 第8卷 第11期 页码 25-28
总结了国外航天运输系统的现状及发展趋势;对比分析了我国长征系列运载火箭的现状和差距;提出了增强我国进入空间能力的五个发展方向,即改进现役运载火箭、研制新一代运载火箭系列、发展快速机动发射小型运载火箭、具备载人登月及深空运输能力、探索重复使用运输技术。
《医学前沿(英文)》 2022年 第16卷 第4期 页码 584-595 doi: 10.1007/s11684-021-0844-7
关键词: hemophilia A adeno-associated virus (AAV) human/rat hybrid factor VIII gene therapy dual chain strategy
The Integration Model of Closed-Loop Supply Chain Resource Allocation Considering Remanufacturing
Xiao-qiu Shi,Yan-yan Li,Wei Long
《工程管理前沿(英文)》 2016年 第3卷 第2期 页码 132-135 doi: 10.15302/J-FEM-2016026
关键词: remanufacturing supply chain reverse logistics resource allocation integration model
Synthesis of ordered cerium-doped cubic mesoporous silica using long-chain ionic liquid as template
YUE Hongxia, ZHAO Hongmei, LIU Longjiang, WANG Siping, Ruan Qiong, WANG Tongwen
《化学科学与工程前沿(英文)》 2008年 第2卷 第2期 页码 135-139 doi: 10.1007/s11705-008-0031-2
关键词: mesoporous CmimCl/Si tendency mesostructure synthesis procedure
Optimal dome design considering member-related design constraints
Tugrul TALASLIOGLU
《结构与土木工程前沿(英文)》 2019年 第13卷 第5期 页码 1150-1170 doi: 10.1007/s11709-019-0543-5
关键词: dome structure geometric nonlinearity multi-objective optimization API RP2A-LRFD
Epidemiological study of a von Hippel-Lindau family in northwest China
null
《医学前沿(英文)》 2013年 第7卷 第3期 页码 378-385 doi: 10.1007/s11684-013-0276-0
von Hippel-Lindau (VHL) disease is a rare, inherited neoplastic disease characterized by hemangioblastomas (HBL) of the central nervous system (CNS), retinal angiomas, renal cell carcinomas (RCC), pancreatic endocrine tumors (PETs), pheochromocytomas, paragangliomas, and visceral cysts. We encountered a large VHL family in northwest China and conducted a systematic screening of the family members based on their epidemiological and clinical characteristics. A self-designed questionnaire was used to collect the general sociodemographic and health information of the family members. For the preliminary family screening, physical examination and abdomen B ultrasonography were performed. The suspected patients were subjected to cranial computerized tomography and fundus examination. The clinical data of the patients with confirmed VHL disease were collected from hospital records. A total of 63 lineal descendants in six generations were observed in the family (generations O, A, B, C, D, E), including 9 dead suspected cases (6 males, 3 females) and 10 living cases (2 males, 8 females). Among the 10 living cases, 4, 2, 1, 3, 4, 8, and 2 manifested HBLs of the CNS, PETs, RCC, pancreatic cysts, renal cysts, pheochromocytomas (4 hemi and 4 bilateral), and paragangliomas, respectively. Data showed that the morbidity of VHL disease in generation C was lower than that in generation B, but the age of onset was younger. This study is the first to report VHL disease in northwest China and VHL-associated PET cases in Chinese. Therefore, follow-up checkups of the family should be focused on younger generations. Proper family screening protocols should be followed for the treatment of patients with VHL disease.
关键词: von Hippel-Lindau disease epidemiology family screening pancreatic endocrine tumor
普列克底物蛋白同源物样结构域家族A成员1蛋白——导致代谢疾病的多方面细胞存活因素 Review
Tamana Yousof, Jae Hyun Byun, Jack Chen, Richard C. Austin
《工程(英文)》 2023年 第20卷 第1期 页码 9-18 doi: 10.1016/j.eng.2022.05.014
普列克底物蛋白同源物样结构域家族A成员1(PHLDA1)是多作用的胞内蛋白,属于进化上保守的普列克底物蛋白同源相关结构域家族。最初,PHLDA1的小鼠同源基因——T 细胞死亡相关51 基因(TDAG51)——因其在T细胞杂交瘤中活化诱导的细胞凋亡中的作用而被发现。近年来,由于PHLDA与肥胖症、脂肪性肝病、糖尿病、动脉硬化和癌症有关,因此受到越来越多的关注。越来越多的证据也证实,PHLDA1在内质网应激信号通路中作为细胞凋亡、自噬和增殖的关键介质发挥作用。本文综述了PHLDA1基因及蛋白调控、定位和功能方面的现有知识。本文重点介绍了PHLDA1促凋亡和抗凋亡,进而导致代谢性疾病的作用。
朵英贤
《中国工程科学》 1999年 第1卷 第2期 页码 57-61
主要叙述我国轻武器行业两代工程技术人员在基础很薄弱的情况下,团结合作,用科学和严密的方法,在很短的时间内研制出高水平的步兵班用枪族,使中国步兵枪械达到世界先进水平,受到军方高度评价。该枪族已于1997年元月正式装备驻港部队,并将陆续装备全军。
Guoxing Chen, Marc Widenmeyer, Binjie Tang, Louise Kaeswurm, Ling Wang, Armin Feldhoff, Anke Weidenkaff
《化学科学与工程前沿(英文)》 2020年 第14卷 第3期 页码 405-414 doi: 10.1007/s11705-019-1886-0
关键词: K2NiF4 structure oxygen permeation membrane CO2 and CO resistances CO2 plasma resistance long-term robustness
《医学前沿(英文)》 页码 1006-1009 doi: 10.1007/s11684-023-1000-3
关键词: family craniofacial microsomia Identification novel mutations
标题 作者 时间 类型 操作
ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling
期刊论文
Keratin 5-Cre-driven deletion of
Jun Yang, Lianqing Wang, Yingzhi Huang, Keqiang Liu, Chaoxia Lu, Nuo Si, Rongrong Wang, Yaping Liu, Xue Zhang
期刊论文
Responses of bacterial strains isolated from drinking water environments to N-acyl-L-homoserine lactones
Zhuoying WU, Qing WANG, Feng GUO, Shenghua ZHANG, Qipei JIANG, Xin YU
期刊论文
Benzene alkylation with long chain olefins catalyzed by ionic liquids: a review
QIAO Congzhen, CAI Yonghong, GUO Quanhui
期刊论文
Continuous reaction performances of benzene alkylation with long chain olefins catalyzed by ionic liquid
QIAO Congzhen, LI Chengyue
期刊论文
Long-term correction of hemorrhagic diathesis in hemophilia A mice by an AAV-delivered hybrid FVIII composedof the human heavy chain and the rat light chain
期刊论文
The Integration Model of Closed-Loop Supply Chain Resource Allocation Considering Remanufacturing
Xiao-qiu Shi,Yan-yan Li,Wei Long
期刊论文
Synthesis of ordered cerium-doped cubic mesoporous silica using long-chain ionic liquid as template
YUE Hongxia, ZHAO Hongmei, LIU Longjiang, WANG Siping, Ruan Qiong, WANG Tongwen
期刊论文
普列克底物蛋白同源物样结构域家族A成员1蛋白——导致代谢疾病的多方面细胞存活因素
Tamana Yousof, Jae Hyun Byun, Jack Chen, Richard C. Austin
期刊论文
A CO and CO
Guoxing Chen, Marc Widenmeyer, Binjie Tang, Louise Kaeswurm, Ling Wang, Armin Feldhoff, Anke Weidenkaff
期刊论文